Pancreatic Organoids in Drug Evaluation: Personalized Models for Precision Medicine
Pancreatic Organoids in Drug Evaluation: Personalized Models for Precision Medicine
The ISCIII Platform for Biomodels and Biobanks presents this specialized webinar, which will take place on Wednesday, April 22, 2026, at 10:00 h. During the session, recent advances in the use of patient-derived pancreatic cancer organoids as experimental platforms to evaluate the efficacy of targeted therapies will be presented. Strategies for modeling tumor heterogeneity, studying drug resistance mechanisms, and developing precision medicine approaches will also be discussed.
The session will be led by Sara Alexandra de Sousa Barrambana, a translational cancer researcher with over 5 years of preclinical experience. She specializes in patient-derived pancreatic cancer models (organoids) and in vivo models, focusing on the evaluation of KRAS-targeted therapies and combination strategies. She integrates functional assays with multi-omic data to identify resistance mechanisms and new therapeutic targets.
Sara holds a degree in Human Biology from the University of Évora. Subsequently, she trained in Molecular Oncology at the University of Porto, where she completed her Master’s thesis (TFM) in the Signaling and Metabolism Group at the Institute for Research and Innovation in Health (i3S). Currently, Sara is finishing her PhD in Molecular Biosciences at the Autonomous University of Madrid. Her thesis has been conducted within the Experimental Oncology Group at the CNIO and has been funded by an FCT grant from the Portuguese government.
Additionally, the event will feature a Q&A and discussion session moderated by Iván Fernández Vega (ISPA-FINBA) and Rocío Aguilar Quesada (BSSPA).
Practical Information
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🔗 Participants: The session is aimed at members of the ISCIII Platform for Biomodels and Biobanks, as well as researchers and platform staff interested in preclinical models and precision medicine in pancreatic cancer.
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🔗 Registration Deadline: Wednesday, April 1st.
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🔗 Webinar Registration: Pre-registration form to receive the connection link.
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🔗 Check Spam Folder: Please check your spam folder after registering to ensure you receive the access link.
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